The effects of folic acid and pyridoxine on performance and yolk 5- methyltetrahydrofolate content of laying quails

Document Type : Research Paper

Authors

1 PhD student, Animal Science Department, Faculty of Agriculture, Urmia University

2 Animal Science Department, Faculty of Agriculture, Urmia University

Abstract

This study was conducted by 360 lying Japanese quail (6 wk old) in a 3*3 factorial arrangement (9 treatments and 5 replicates each) to investigate the effects of folic acid (0.0, 4.0 or 8.0 mg/kg) and pyridoxine (0.0, 0.3 or 6 mg/kg) on laying performance and egg yolks 5-methyl tetrahydrofolate content. The results showed that folic acid or pyridoxine had no effects on feed intake, egg production, feed conversion ratio, yolk and white percentage, egg content weight and haugh unit of the eggs (P>0.05).The 5- methyl tetrahydrofolate content of the eggs was affected by folic acid supplementation and it was increased from 808.62 microgarm/g for control birds to 840.84 and 1164.77 microgarm/g respectivly for 4 and 8 mg/kg folic acid fed birds (P<0.01). In conclusion, dietary supplementation of folic acid to lying Japanese quail diets had no effects on performance but consumption of 8 mg/kg folic acid increases the 5-methyl tetrahydrofolate content of yolk.
Key Words: Folic acid, Japanese quail, pyridoxine, performance, 5-methyltetrahydrofolate.

Keywords


خاکپور ایرانی، ف. (1391). بررسی اثرات سطوح مختلف لیزین و پیریدوکسین یر عملکرد، خصوصیات لاشه و وضعیت آنتی­ اکسیدانی بدن جوجه­های گوشتی تحت استرس گرمایی. پایان نامه کارشناسی ارشد،  دانشکده کشاورزی دانشگاه ارومیه.
باقری، س.، جانمحمدی، ح.، ملکی، ر.، استاد رحیمی، ع.، و کیانفر، ر. (1395). اثرات افزودن اسید فولیک و روی بر محتوای 5-متیل تترا هیدروفولات زرده، کیفیت تخم مرغ و عملکرد مرغ های تخمگذار
Paul, M. C., Joseph M. B., Marc R. B., Gordon M. C., Mark, L., Joel, M. and Jeffrey D.W. (2010). Folate. In Encyclopedia of Dietary Supplements.
 CRC Press , New York. 219-228.
Beatty, P.W. and Reed, D.J. (1980). Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes. Archives of biochemistry and biophysics. 204:80-87.
Bunchasak, C and Kachana, S. (2009). Dietary folate and vitamin B12 supplementation and consequent vitamin deposition in chicken eggs. Tropical Animal Health and Production. 41:1583-1589.
Daghir N. J and Haddad K. S. (1981). Vitamin B6 in the etiology of gizzard erosion in growing chickens. Poultry Science. 60: 988-992.
Dickson, T.M., Tactacan; G.B., Hebert; K., Guenter, W. and House, J.D. (2010). Optimization of folate deposition in eggs through dietary supplementation of folic acid over the entire production cycle of Hy-Line W36, Hy-Line W98, and CV20 laying hens. The journal of applied poultry research. 19:80-91.
Hebert, K; House, J.D. and Guenter, W. (2005). Effect of dietary folic acid supplementation on egg folate content and the performance and folate status of two strains of laying hens. Poultry Science. 84:1533-1538.
Henderson, G.B. (1990). Folae-Binding proteins. Annual review of nutrition. 10:3 19-335.
Henk, J.B. and Yvo, S. (2011). Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects. Journal of inherited metabolic disease. 34:75-81.
Herbert, V. (1987). Recommended dietary intakes (RDI) of folate in humans. The American journal of clinical nutrition. 45(4):661-670.
Hoey L.1., McNulty H., McCann E.M., McCracken K.J., Scott J.M., Marc B.B., Molloy A.M., Graham, C. and Pentieva K. (2009). Laying hens can convert high doses of folic acid added to the feed into natural folates in eggs providing a novel source of food folate. The British journal of nutrition. 101:206-212.
House, J.D., Braun, K., Balance, D.M., O'Connor, C.P. and. Guenter, W. (2002). The enrichment of eggs with folic acid through supplementation of laying hen diet. Poultry Science. 81:1332-1337.
House, J.D.; O‟Connor, C.P.; and Guenter, W. (2003). Plasma homocysteine and glycine are sensitive indices of folate status in a rodent model of folate depletion and repletion. Journal of agricultural and food chemistry. 51:4461-4467.
Keshavarz, K. (2003). Effects of reducing dietary protein, methionine, choline, folic acid, and vitamin B12 during the late stages of the egg production cycle on performance and eggshell quality. Poultry Science. 82:1407-1414.
Lima, C.P., Davis, S.R., Mackey, A.D., Scheer, J.B., Williamson, J and Gregory J.F. III.(2006). Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G diets. The Journal of nutrition. 136:2141-2147.
Martinez, M., Cuskelly, G.J., Williamson, J., Toth, J.P. and Gregory J.F. (2000). Vitamin B-6 deficiency in rats reduces hepatic serine hydroxymethyltransferase and cystathionine β-synthase activities and rates of in vivo protein turnover, homocysteine remethylation and transsulfuration. The Journal of nutrition. 130:1115-1123.
McDowell L.R. (2000). Vitamins in animal and human nutrition. Second edition. Lowa State University Press.
Mudd, S.H. and Poole, J.R. (1975). Labile methyl balances for normal humans on various dietary regimes. Metabolism: clinical and experimental. 24: 721-735.
NRC. (1994). Nutrient requirements of poultry, 9th rev ed. National Research council, National Academy Press, Washington, DC.
Sadegheymojarad, R., Farhomand, P. and Daneshyar, M. (2018). Effect of dietary betaine and folic acid supplementation on performance, egg folate content and egg production of Japanese quail. Iranian Journal of Applied Animal Science (IJAS), in­ prees.
Scott M. L., Nesheim M.C. and Young R.J. (1982). Nutrition of the chicken.. Scott, Ithaca, New York. P. 119
Selhub, J. and Rosenberg, I.H. (1996). Folic acid. In "Present Knowledge in Nutrition" (E.E. Ziegler and L.J. Filer, Jr., eds), 7th ed., ILSI Press, Washington, D.C. papers. 206-219.
Sahin, K.M., Onderci, M., Sahin, N., Gursu, M.F., Kucuk, O. (2003). Dietary vitamin C and folic acid supplementation Ameliorates the detrimental effects off heat stress in Japanese quail. The Journal of nutrition. 133: 1882-1886.
Sherwood, T.A.; Alphin; R.L., Saylor W.W. and White, H.B. III. (1993). Folate metabolism and deposition in eggs by laying hens. Archives of biochemistry and biophysics. 307:66-72.
Tactacan, G.B, Jing, M., Thiessen, S., Rodriguez-Lecompte, J.C, O‟Connor, D.L., Guenter, W. and House, J.D. (2010). Characterization of folate-dependent enzymes and indices of folate status in laying hens supplemented with folic acid or 5-methyltetrahydrofolate. Poultry. Science. 89:688-696.
Weise F.G. (1976). An investigation of the role of fiber, Kilocalories and vitamin B6 on serum and egg cholesterol in the laying hen. M. Sc, Thesis, Cornell Univ.